The company is Austrian high-tech R&D SME with a multidisciplinary team of ~20 employees that includes system and applied data scientists, physical world system modelers, developers of backend/frontend software, and mobile and web app, designers, testers. It has core sales, support staff, own cloud development infrastructure managed from its Vienna office. GOLEM collaborates with United Nations Industrial Development Organization (UNIDO) as outsourcing partner supporting Pharos Navigator® platform applications for sustainable green Agri-Industrial developments, provision of healthy food, biomass and energy for its international programs in Africa, Latin America and Asia. AT the initial stages of its business the company collaborated with several major large international corporations (Siemens, Texas Instruments, etc.) as system integrator and reseller. Applying its strong expertise in system sciences, process control, ICT and IoT driven by AI and Big Data methodologies, GOLEM team formulated radically new approach toward modelling of complex cyber-bio-physical systems and developed dedicated software platform prototype Pharos Navigator® (PharosN TRL6/7) based only on open source software components. The unique innovation allows rapid development of disruptive large scale integrated high level applications for intelligent management, monitoring and control of complex real-world systems, operations and processes in different areas such as Digital Health, Enterprises, Energy, Smart Homes/Buildings, Smart Cities, Environment, etc. Based on the innovation results the company focuses its business development to address challenges of holistic health monitoring and management and provide practical cutting-edge scalable solutions enabling transition to new generation of digital care ecosystem in EU.